Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity related to bortezomib, a proteasome inhibitor used in the therapy of numerous myeloma. Its synthesis or examine is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-1): A key compound during the synthesis of imatinib, a drug that targets precise forms of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the creation course of action and guaranteeing large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilised to take care of breast most cancers, and these intermediates are involved with its creation.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Docetaxel intermediate Employed in the procedure of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug successful in managing cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the cure of colorectal cancer and compact cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is associated with the synthesis of adamantane derivatives, which have various programs, together with antiviral Attributes.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide an oral drug for type 2 diabetes that inhibits the enzyme DPP-4 to regulate blood sugar stages.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is linked to the synthesis of assorted gluconic acid derivatives, which can be Utilized in food items, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).